ACO2 anticorps (C-Term)

N° du produit ABIN4886417

L’anticorps Lapin Polyclonal anti-ACO2 a été validé pour WB. Il convient pour détecter ACO2 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour ACO2 anticorps (C-Term) (ABIN4886417)

Antigène: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACO2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ACO2 anticorps

Épitope: AA 561-596, C-Term

Fonction: Anti-Aconitase 2/ACO2 Antibody Picoband®

Séquence: TSQRLQLLEP FDKWDGKDLE DLQILIKVKG KCTTDH

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Aconitase 2/ACO2 Antibody Picoband® (ABIN4886417). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Aconitase 2, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: Aconitase 2, mitochondrial". 2. Geurts van Kessel, A. H. M., Westerveld, A., de Groot, P. G., Meera Khan, P., Hagemeijer, A. Regional localization of the genes coding for human ACO2, ARSA, and NAGA on chromosome 22. Cytogenet. Cell Genet. 28: 169-172, 1980. 3. Mirel, D. B., Marder, K., Graziano, J., Freyer, G., Zhao, Q., Mayeux, R., Wilhelmsen, K. C. Characterization of the human mitochondrial aconitase gene (ACO2). Gene 213: 205-218, 1998.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur ACO2

Antigène: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Autre désignation: ACO2

Sujet:

Synonyms: Aconitate hydratase, mitochondrial,Aconitase,4.2.1.3,Citrate hydro-lyase,ACO2,

Tissue Specificity: Highly enriched in the brain. Much weaker expression in heart, lung and muscle.

Background: Aconitase 2, mitochondrial is a protein that in humans is encoded by the ACO2 gene. The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.

Poids moléculaire: 85 kDa

ID gène: 50

UniProt: Q99798